Enzymes that cut DNA at specific sites are called endonucleases; these enzymes play many roles in genomic replication, fidelity, and defense. The initial discovery of restriction endonucleases in the ...

The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a UCL-led research team. DNA is widely accepted to be formed of two strands that wind around one ...

Scientists have found that twisting structures in DNA long mistaken for knots are actually something else entirely. Inside cells, DNA gets twisted, copied, and pulled apart. The twists can influence ...

In 1963, Popular Science reported on the Nobel Prize-winning discovery, and the woman who was left out of the accolades. By Bill Gourgey Published May 31, 2022 7:00 AM EDT Get the Popular Science ...

In the middle of the 20th century, accumulating data suggested that DNA carries life’s genetic information. Biochemists around the world raced to determine its structure. The competition led to some ...

As imaging tools continue to get more sophisticated, researchers have been able to actually watch biological processes as they are happening in live cells. Scientists have now visualized loops of DNA ...

DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes. Among them, DNA–histone cross-links (DHCs) occur frequently within ...

No "sticky ends"? No problem. A new study by NYU chemists finds that DNA tiles can assemble into 3D structures without the sticky cohesion of hydrogen bonding. This finding, published in Nature ...

Maize serves as a vital model species for advancing our understanding of plant biology, yet many mysteries remain about the ...